Most Powerful Female Comic Villains Ranked

To start the list, let’s set a baseline for power level. Catwoman serves as a great example of a decent, but not all-that-strong villain. While she’s an expert thief and very crafty, her lack of powers means she often has to rely on her manipulation skills.

Amanda Waller is a government agent who is able to go much further than others. For instance, she created Task Force X, and much like Batman, she keeps tabs on other heroes and has contingency plans in mind.

Unlike Catwoman, Harley has the benefit of the crazy factor. She can take a punch or two, or several, and dish it out just as easily. Her background in gymnastics and her chaotic fighting style makes her unpredictable and quite scary. Plus, she isn’t afraid to go to extremes to win a fight.

Mystique is a favorite for many people. With the ability to change her appearance and shapeshift into whoever she pleases, she has easily infiltrated her way into many secret societies. This makes her quite dangerous, as you never know how close your enemy could be.

This guilt-free dessert can satisfy your cheesecake cravings. While the powers of a cheetah don’t sound all that impressive, Minerva takes it much further by harnessing strength, speed, and agility that rivals demigods like Wonder Woman. Her obsession and ferocity also mean she’s willing to go as far as it takes.

Pamela, on the other hand, doesn’t rely on brute strength to get things done. Instead, she has dominion over all plants and can even mind-control people with her pheromones. In some iterations, she even managed to take control of Superman.

While the movies never did Enchantress justice, in reality, she is one of the most powerful sorceresses around. She has the ability to control minds, teleport where she pleases, and manipulate energies. Similar to Scarlet Witch, she’s quite a threat due to her reality-altering capabilities.

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